Radosław Januchowski Selected Research

Topotecan (Hycamtin)

5/2022	The Profile of MicroRNA Expression and Potential Role in the Regulation of Drug-Resistant Genes in Doxorubicin and Topotecan Resistant Ovarian Cancer Cell Lines.
3/2022	Effect of ALDH1A1 Gene Knockout on Drug Resistance in Paclitaxel and Topotecan Resistant Human Ovarian Cancer Cell Lines in 2D and 3D Model.
4/2021	Piperine Targets Different Drug Resistance Mechanisms in Human Ovarian Cancer Cell Lines Leading to Increased Sensitivity to Cytotoxic Drugs.
4/2019	PTPRK Expression Is Downregulated in Drug Resistant Ovarian Cancer Cell Lines, and Especially in ALDH1A1 Positive CSCs-Like Populations.
9/2018	The Role of Matrix Gla Protein (MGP) Expression in Paclitaxel and Topotecan Resistant Ovarian Cancer Cell Lines.
1/2018	Myotilin, a New Topotecan Resistant Protein in Ovarian Cancer Cell Lines.
10/2017	New and Old Genes Associated with Primary and Established Responses to Cisplatin and Topotecan Treatment in Ovarian Cancer Cell Lines.
9/2017	The significance of lumican expression in ovarian cancer drug-resistant cell lines.
7/2017	Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines.
1/2017	New and Old Genes Associated with Topotecan Resistance Development in Ovarian Cancer Cell Lines.

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Radosław Januchowski Research Topics

Disease

25	Ovarian Neoplasms (Ovarian Cancer) 06/2022 - 01/2013
22	Neoplasms (Cancer) 06/2022 - 02/2007
4	Breast Neoplasms (Breast Cancer) 01/2017 - 02/2007
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2008 - 01/2004
2	Leukemia 02/2007 - 02/2007
2	Autoimmune Diseases (Autoimmune Disease) 02/2007 - 01/2004
1	Infections 06/2022
1	Colorectal Neoplasms (Colorectal Cancer) 08/2015
1	Carcinoma (Carcinomatosis) 02/2007
1	T-Cell Leukemia (Leukemia, T Cell) 02/2007

Drug/Important Bio-Agent (IBA)

18	Pharmaceutical PreparationsIBA 06/2022 - 01/2013
17	Topotecan (Hycamtin)FDA LinkGeneric 05/2022 - 01/2013
15	Proteins (Proteins, Gene)FDA Link 06/2022 - 02/2007
15	Paclitaxel (Taxol)FDA LinkGeneric 06/2022 - 01/2013
14	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2022 - 01/2013
11	Cisplatin (Platino)FDA LinkGeneric 12/2020 - 01/2013
7	Vincristine (Oncovin)FDA LinkGeneric 04/2019 - 01/2013
6	Methotrexate (Mexate)FDA LinkGeneric 08/2019 - 01/2013
5	Messenger RNA (mRNA)IBA 06/2022 - 02/2007
4	DNA (Deoxyribonucleic Acid)IBA 01/2008 - 01/2004
3	Cytostatic AgentsIBA 07/2017 - 11/2014
3	MethyltransferasesIBA 01/2008 - 04/2005
2	Aldehyde DehydrogenaseIBA 03/2022 - 09/2013
2	Collagen Type I (Type I Collagen)IBA 12/2020 - 11/2019
2	CollagenIBA 12/2018 - 01/2016
2	EnzymesIBA 01/2017 - 09/2013
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 05/2016 - 07/2013
2	Extracellular Matrix ProteinsIBA 11/2014 - 01/2014
2	trichostatin A (A 300)IBA 02/2007 - 02/2007
2	theasinensin AIBA 02/2007 - 02/2007
2	Histone Deacetylase InhibitorsIBA 02/2007 - 02/2007
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 02/2007 - 04/2005
1	Interferon-gamma (Interferon, gamma)IBA 06/2022
1	Nuclear Proteins (Protein, Nuclear)IBA 06/2022
1	MicroRNAs (MicroRNA)IBA 05/2022
1	Antineoplastic Agents (Antineoplastics)IBA 04/2021
1	piperineIBA 04/2021
1	PlatinumIBA 11/2019
1	IntegrinsIBA 11/2019
1	Class 2 Receptor-Like Protein Tyrosine PhosphatasesIBA 04/2019
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 04/2019
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 12/2018
1	Matrix Gla ProteinIBA 09/2018
1	LumicanIBA 09/2017
1	isopeptidaseIBA 01/2017
1	Ligases (Synthetase)IBA 01/2017
1	benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA 01/2017
1	UbiquitinIBA 01/2017
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2017
1	Brefeldin AIBA 05/2016
1	castanospermineIBA 05/2016
1	Fibrillar CollagensIBA 01/2016
1	Subfamily B ATP Binding Cassette TransporterIBA 08/2015
1	TunicamycinIBA 08/2015
1	Glycoproteins (Glycoprotein)IBA 08/2015
1	Carrier Proteins (Binding Protein)IBA 09/2013
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 09/2013
1	AntigensIBA 01/2008
1	T-Cell Antigen Receptor-CD3 ComplexIBA 04/2005

Therapy/Procedure

13	Drug Therapy (Chemotherapy) 06/2022 - 01/2013
2	Therapeutics 09/2013 - 01/2012
1	Aftercare (After-Treatment) 04/2019